Anti-Growth Hormone Antibody [GH/4886R] - BSA and Azide free
Description du produit
Recombinant rabbit monoclonal [GH/4886R] antibody to Growth Hormone.
Spécificité
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human Growth Hormone.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
GH/4886R
Isotype
IgG
Conjuguer
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
20 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Negative Tissue Control: Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain using Anti-Growth Hormone Antibody [GH/4886R] at 2µg/ml in PBS for 30 minutes at room temperature.
SDS-PAGE analysis of Anti-Growth Hormone Antibody [GH/4886R] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
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