Recombinant Anti-GP2 Anticorps [rGP2/8617] (A316429)

$765

Anticorps monoclonal [rGP2/8617] de souris contre GP2 pour ELISA, WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-GP2 Antibody [rGP2/8617] - BSA and Azide free
Description du produit
Recombinant mouse monoclonal [rGP2/8617] antibody to GP2.
Spécificité
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Applications
ELISA, WB, IHC-P
Contrôle positif
PANC-1 cells. Human pancreas.
Recommander des dilutions
ELISA: 2-4 µg/ml for coating, WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment of human GP2 protein (around Amino Acids 35-179). The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rGP2/8617
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
Predicted 59 kDa / Observed 100 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
GCTM-2 antigen, Gp200, MGC138240, PC, PCLP, PCLP-1, PCLP1, Pcx, Podocalyxin, Podocalyxin like, Podocalyxin like protein, Podocalyxin-like protein 1, PODXL, PODXL_HUMAN
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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