Anti-GP2 Antibody [GP2/3510] - BSA and Azide free (A316428)

Anti-GP2 Antibody [GP2/3510] - BSA and Azide free

Mouse monoclonal [GP2/3510] antibody to GP2.

GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

ELISA, WB, IHC-P

PANC-1 cells. Human pancreas.

ELISA: 2-4 µg/ml for coating, WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment of human GP2 protein (around Amino Acids 35-179). The exact sequence is proprietary.

Mouse

Monoclonal

GP2/3510

kappa

Protein A/G chromatography.

1 mg/ml

Predicted 59 kDa / Observed 100 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

DKFZp779K0533, Glycoprotein 2 (zymogen granule membrane), GP2_HUMAN, Pancreatic secretory granule membrane major glycoprotein GP2, Pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75