Anti-GnRHR Anticorps [F1G4] (A251924)

Name: Anti-GnRHR Antibody [F1G4] - BSA and Azide free
Brand: Antibodies.com
SKU: A251924
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [F1G4] de souris contre GnRHR pour Flow Cytometry, IF, WB et IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Spécifications

Nom du produit

Anti-GnRHR Antibody [F1G4] - BSA and Azide free

Description du produit

Mouse monoclonal [F1G4] antibody to GnRHR.

Spécificité

This antibody recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.

Applications

Flow Cytometry, IF, WB, IHC-P

Recommander des dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivité

Human, Rat

Réactivité croisée

This antibody is predicted to cross react with Porcine and Rabbit.

Immunogène

Synthetic peptide corresponding to amino acids 1-29 of human GnRH receptor.

Séquence

MANSASPEQNQHCSAINNSIPLMQGNLPY

Hôte

Mouse

Clonalité

Monoclonal

Clone

F1G4

Isotype

IgG1

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Masse moléculaire

54-60 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-GnRHR Antibody [F1G4] (A248742).

Synonymes

GnRH receptor, GnRH-R, GNRHR1, GNRHR_HUMAN, Gonadotropin releasing hormone receptor, gonadotropin-releasing hormone (type 1) receptor 1, Gonadotropin-releasing hormone receptor, GRHR, HH7, leutinizing-releasing hormone receptor, lh-rh, LHRHR, LRHR, luliberin receptor, luteinizing hormone releasing hormone receptor, type I GnRH receptor

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (3)

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Figure 1: Immunohistochemistry - Anti-GnRHR Antibody [F1G4] - BSA and Azide free (A251924)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human ovarian tumor using Anti-GnRHR Antibody [F1G4].

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Figure 2: Western Blot - Anti-GnRHR Antibody [F1G4] - BSA and Azide free (A251924)

Western blot analysis of human MDA-231 cell lysate using Anti-GnRHR Antibody [F1G4].

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Figure 3: Immunofluorescence - Anti-GnRHR Antibody [F1G4] - BSA and Azide free (A251924)

Immunofluorescent analysis of MCF-7 cells stained with Anti-GnRHR Antibody [F1G4] followed by Goat Anti-Mouse IgG (CF® 488) (Green). The nuclear counterstain is RedDot (Red).