Anti-GCET2 Anticorps [HGAL/2373] (A277621)

Anticorps monoclonal [HGAL/2373] de souris contre GCET2 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-GCET2 Antibody [HGAL/2373]
Description du produit
Mouse monoclonal [HGAL/2373] antibody to GCET2.
Spécificité
This antibody recognizes a protein of kDa, which is identified as HGAL. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 1-200, of human GCET2 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
HGAL/2373
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
21 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-GCET2 Antibody [HGAL/2373] - BSA and Azide free (A278209).
Synonymes
GCAT2, Gcet, GCET2 germinal center expressed transcript 2, GCET2 germinal centre expressed transcript 2, Gcsam, GCSAM_HUMAN, Germinal center associated lymphoma, Germinal center associated lymphoma protein, Germinal center B cell associated protein 2, Germinal center B-cell-expressed transcript 2 protein, Germinal center expressed transcript 2, Germinal center-associated lymphoma protein, Germinal center-associated signaling and motility protein, Germinal centre associated lymphoma, Germinal centre associated lymphoma protein, Germinal centre B cell associated protein 2, Germinal centre expressed transcript 2, hGAL, M17, M17 L
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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