Anti-GATA4 Anticorps [PCRP-GATA4-1A7] (A316379)

$765

Anticorps monoclonal [PCRP-GATA4-1A7] de souris contre GATA4 pour Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-GATA4 Antibody [PCRP-GATA4-1A7] - BSA and Azide free
Description du produit
Mouse monoclonal [PCRP-GATA4-1A7] antibody to GATA4.
Spécificité
Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4, expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
Applications
Flow Cytometry
Contrôle positif
HeLa or MCF-7 cells.
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 262-321) of human GATA4 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-GATA4-1A7
Isotype
IgG2b
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
44.57 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
ASD2, GATA 4, GATA binding protein 4, GATA-binding factor 4, GATA4_HUMAN, MGC126629, Transcription factor GATA 4, Transcription factor GATA-4, Transcription factor GATA4, VSD1
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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