Recombinant Anti-FOXA1 Anticorps [rFOXA1/1515] (A248860)

Anticorps monoclonal [rFOXA1/1515] de souris contre FOXA1 pour Flow Cytometry et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-FOXA1 Antibody [rFOXA1/1515]
Description du produit
Recombinant mouse monoclonal [rFOXA1/1515] antibody to FOXA1.
Spécificité
The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors.HNF-1 (), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
Applications
Flow Cytometry, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml
Reactivité
Human, Rat
Immunogène
Recombinant fragment, around amino acids 372-472, of human FOXA1 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rFOXA1/1515
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
49 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-FOXA1 Antibody [rFOXA1/1515] - BSA and Azide free (A252040).
Synonymes
forkhead box A1, Forkhead box protein A1, FOX A1, FOXA1_HUMAN, hepatocyte nuclear factor 3 alpha, Hepatocyte nuclear factor 3-alpha, HNF 3A, HNF-3-alpha, HNF-3A, HNF3A, MGC33105, TCF 3A, TCF-3A, TCF3A, Transcription factor 3A
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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