Anti-FLIP Antibody (A283850)

Anti-FLIP Antibody

Rabbit polyclonal antibody to FLIP.

This antibody recognises the ~55 kDa FLIPL protein, a FLICE inhibitory protein.FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors.FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by Rabbit anti Human FLIP L antibody (AHP430).

WB, IHC-Fr

WB: 1:500 - 1:2,000

Human

A peptide corresponding to a region at the C-terminus of human FLIPL.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human FLIP L antibody recognizes the ~55 kDa FLIPL protein, a FLICE inhibitory protein.FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors.FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by Rabbit anti Human FLIP L antibody (AHP430).

c-FLIP, CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, CFLAR, CLARP, FADD-like antiapoptotic molecule 1, FLAME-1, MRIT