Anti-FGF 23 Antibody [FGF23/131] (A314964)

Anti-FGF 23 Antibody [FGF23/131]

Mouse monoclonal [FGF23/131] antibody to FGF 23.

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

WB, IHC-P

Human kidney tissue.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant full-length human FGF23 protein.

Mouse

Monoclonal

FGF23/131

Protein A/G chromatography.

200 µg/ml

12-32 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

FGF-23, Fibroblast growth factor 23, HYPF, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor