Anti-Factor VII Anticorps [F7/3512] (A314947)

$765

Anticorps monoclonal [F7/3512] de souris contre Factor VII pour ELISA et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Factor VII Antibody [F7/3512]
Description du produit
Mouse monoclonal [F7/3512] antibody to Factor VII.
Spécificité
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels.
Applications
ELISA, IHC-P
Contrôle positif
Human liver or gastric carcinoma.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 366-466) of human F7 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
F7/3512
Isotype
IgG2
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
200 kDa / 80 kDa / 73 kDa / 50 kDa / 43 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
Cf7, Coagulation factor VII, coagulation factor VII (serum prothrombin conversion accelerator), Eptacog alfa, F7, F7 deficiency, FA7_HUMAN, Factor VII deficiency, Factor VII heavy chain, Factor VII light chain, FVII, FVII coagulation protein, Hypoproconvertinemia, OTTHUMP00000018733, OTTHUMP00000018734, Proconvertin, Serum prothrombin conversion accelerator, SPCA
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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