Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] - BSA and Azide free
Description du produit
Mouse monoclonal [CPTC-SULT1E1-1] antibody to Estrogen Sulfotransferase.
Spécificité
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
Applications
WB, IHC-P
Recommander des dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human SULT1E1 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
CPTC-SULT1E1-1
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
35 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human small intestine using Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1].
SDS-PAGE analysis of Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.