Anti-ERCC1 Anticorps [ERCC1/7596] (A316306)

$765

Anticorps monoclonal [ERCC1/7596] de souris contre ERCC1 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-ERCC1 Antibody [ERCC1/7596] - BSA and Azide free
Description du produit
Mouse monoclonal [ERCC1/7596] antibody to ERCC1.
Spécificité
Recognizes a protein of 110kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
Applications
IHC-P
Contrôle positif
HeLa or HepG2 cells. Tonsil or Prostate.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 191-281) of human ERCC1 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
ERCC1/7596
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
110 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
COFS 4, COFS4, DNA excision repair protein ERCC 1, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC1, ERCC 1, ERCC1_HUMAN, Excision repair cross complementation group 1, Excision repair cross complementing 1, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1, Excision repair protein, RAD 10, RAD10, UV 20, UV20
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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