Anti-ERCC1 Antibody [ERCC1/2683] (A248463)

Mouse monoclonal [ERCC1/2683] antibody to ERCC1 for ELISA and WB.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-ERCC1 Antibody [ERCC1/2683]
Description
Mouse monoclonal [ERCC1/2683] antibody to ERCC1.
Specificity
This antibody recognizes a protein of 110kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
Applications
ELISA, WB
Dilutions
WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 191-281, of human ERCC1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
ERCC1/2683
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
110 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ERCC1 Antibody [ERCC1/2683] - BSA and Azide free (A251645).
Synonyms
DNA excision repair protein ERCC-1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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