Rabbit polyclonal antibody to eIF4EBP1 (phospho Ser65).
Applications
WB
Recommander des dilutions
WB: 1:500 - 1:2,000
Reactivité
Human, Mouse, Rat
Immunogène
Phospho-specific peptide corresponding to residues surrounding Ser65 of human 4EBP1.
Hôte
Rabbit
Clonalité
Polyclonal
Isotype
IgG
Conjuguer
Unconjugated
Concentration
Lot Specific
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Stockage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) is also known as phosphorylated heat-and acid-stable protein regulated by insulin 1 (PHAS-I), when phosphorylated at serine 65. 4EBP1 belongs to the eIF4E-binding protein family. 4EBP1, when bound to eIF4E, inhibits cap-dependent translation. Phosphorylation at serine 65 inhibits binding of 4EBP1 to eIF4F allowing cap-dependent translation.
Synonymes
4E-BP1, 4EBP1, 4EBP1_HUMAN, BP 1, eIF4E binding protein 1, eIF4E-binding protein 1, Eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I, PHASI, Phosphorylated heat- and acid-stable protein regulated by insulin 1
