Anti-E2F6 Anticorps [PCRP-E2F6-1F8] (A251562)

Anticorps monoclonal [PCRP-E2F6-1F8] de souris contre E2F6 pour Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-E2F6 Antibody [PCRP-E2F6-1F8] - BSA and Azide free
Description du produit
Mouse monoclonal [PCRP-E2F6-1F8] antibody to E2F6.
Spécificité
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human E2F6 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-E2F6-1F8
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
35 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-E2F6 Antibody [PCRP-E2F6-1F8] (A254378).
Synonymes
E2F 6, E2F binding site modulating activity protein, E2F transcription factor 6, E2F transcription factor 6 isoform 1, E2F-6, E2F6_HUMAN, EMA, MGC111545, Transcription factor E2F6
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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