Anti-Dopamine beta Hydroxylase Anticorps [DBH/7224] (A316278)

$765

Anticorps monoclonal [DBH/7224] de souris contre Dopamine beta Hydroxylase pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Dopamine beta Hydroxylase Antibody [DBH/7224] - BSA and Azide free
Description du produit
Mouse monoclonal [DBH/7224] antibody to Dopamine beta Hydroxylase.
Spécificité
Dopamine -hydroxylase (DBH) catalyzes the conversion of dopamine to noradrenaline in the biosynthesis of catecholamines. DBH is selectively expressed in noradrenergic and adrenergic neurons, as well as in neuroendocrine cells, and it serves as a specific protein marker for noradrenergic processes. The active form of DBH is a homotetramer, which is found in the lumen of synaptic vesicles of corresponding nerve cells, where it localizes to both the membrane and cytosol. DBH is induced by nerve growth factor and Insulin growth factor-1 and is regulated by intracellular second messengers protein kinase A, cyclic AMP, diacyl glycerol and Ca2+. Expression of DBH is transcriptionally mediated by Sp1, CREB and AP-1 proteins including c-Fos, c-Jun and JunD.
Applications
IHC-P
Contrôle positif
Human adrenal gland or adrenal pheochromocytoma.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 200-400) of human DBH protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
DBH/7224
Isotype
IgG2
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
78 kDa / 84 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
dbh, DBM, Dopamine beta monooxygenase, Dopamine beta-hydroxylase (dopamine beta-monooxygenase), Dopamine beta-monooxygenase, DOPO_HUMAN, OTTHUMP00000022501, Soluble dopamine beta-hydroxylase
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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