Anti-Desmoglein 3 Anticorps [DSG3/2839] (A248379)

Anticorps monoclonal [DSG3/2839] de souris contre Desmoglein 3 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Desmoglein 3 Antibody [DSG3/2839]
Description du produit
Mouse monoclonal [DSG3/2839] antibody to Desmoglein 3.
Spécificité
This antibody recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 379-491, human DSG3 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
DSG3/2839
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
130 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Desmoglein 3 Antibody [DSG3/2839] - BSA and Azide free (A251561).
Synonymes
130 kD pemphigus vulgaris antigen, 130 kDa pemphigus vulgaris antigen, Balding, Cadherin family member 6, CDHF 6, CDHF6, Desmoglein 3 precursor, Desmoglein-3, Desmoglein3, DKFZp686P23184, DSG 3, DSG3, DSG3_HUMAN, Pemphigus vulgaris antigen, PVA
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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