Anti-DcR3 Anticorps (A283154)

Anticorps polyclonal de lapin contre DcR3 pour WB et IHC-P.

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-DcR3 Antibody
Description du produit
Rabbit polyclonal antibody to DcR3.
Spécificité
This antibody recognises the amino Terminal of human DcR3, otherwise known as Decoy Receptor 3, a ~33 kDa member of the tumour necrosis factor receptor superfamily. DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis. DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung. It may also be found in fetal lung, brain and liver and is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Applications
WB, IHC-P
Recommander des dilutions
IHC-P 1: 1 µg/ml, WB: 0.5 - 1 µg/ml
Reactivité
Human, Mouse, Rat
Immunogène
A peptide corresponding to amino acids near the N-terminus of human DcR3 precursor.
Hôte
Rabbit
Clonalité
Polyclonal
Isotype
IgG
Conjuguer

Unconjugated

Concentration
500 µg/ml
Masse moléculaire
Approximately 33 kDa in human heart lysate.
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Notes générales
Rabbit anti Human DcR3 (N-Terminal) antibody recognizes the amino Terminal of human DcR3, otherwise known as Decoy Receptor 3, a ~33 kDa member of the tumour necrosis factor receptor superfamily. DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis. DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung. It may also be found in fetal lung, brain and liver and is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Synonymes
Decoy receptor 3, Decoy receptor for Fas ligand, DJ583P15.1.1, M68, M68E, OTTHUMP00000031583, TNF6B_HUMAN, TNFRSF6B, TR6, Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor receptor superfamily member 6b decoy, UNQ186/PRO212
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
Haut