This antibody recognises human Deleted in azoospermia-like, also known as DAZL, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1 or SPGY-like-autosomal. DAZL is a 295 amino acid ~33 kDa member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is predominantly localized to the cytoplasm.Mutations in this gene have been linked to severe spermatogenic failure and infertility in males

Applications

WB, IHC-P, IF

Reactivité

Human, Mouse, Rat, Cynomolgus monkey

Immunogène

Synthetic peptide sequence CRVHHFRRSRAMLKSV from within the C-terminus of human DAZL.

Séquence

CRVHHFRRSRAMLKSV

Hôte

Mouse

Clonalité

Monoclonal

Clone

3/11A

Isotype

IgG1

Conjuguer

Unconjugated

Concentration

Lot Specific

Pureté

Tissue Culture Supernatant containing 0.1M Tris/HCl

Forme du produit

Liquid

Formulation

Supplied in <0.1% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Mouse anti Human DAZL antibody, clone 3/11A recognizes human Deleted in azoospermia-like, also known as DAZL, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1 or SPGY-like-autosomal. DAZL is a 295 amino acid ~33 kDa member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is predominantly localized to the cytoplasm.Mutations in this gene have been linked to severe spermatogenic failure and infertility in males (Lin et al. 2001)

Synonymes

DAZ homolog, DAZ like autosomal, DAZ-like autosomal, DAZH, DAZL 1, DAZL1, DAZLA, DAZL_HUMAN, Deleted in azoospermia like, Deleted in azoospermia like 1, Deleted in azoospermia like autosomal, Deleted in azoospermia-like, Deleted in azoospermia-like 1, Germline specific RNA binding protein, MGC26406, Spermatogenesis gene on the Y like autosomal, SPGY like autosomal, SPGY-like-autosomal, SPGYLA, Tpx2

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.