Recombinant rabbit monoclonal [KRT1/8342R] antibody to Cytokeratin 1.
Specificity
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
Applications
IHC-P
Positive Control
Human skin or cervix.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human KRT1 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
KRT1/8342R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
67 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
67 kDa cytokeratin, CK-1, CK-10, Cytokeratin-1, Cytokeratin-10, Hair alpha protein, K1, K10, Keratin, type I cytoskeletal 10, Keratin, type II cytoskeletal 1, Keratin-1, Keratin-10, KPP, KRT1, KRT10, KRTA, Type-II keratin Kb1
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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