Anti-CX3CL1 Anticorps (Biotin) (A282346)

Anti-CX3CL1 Antibody (Biotin) - BSA and Azide free

Rabbit polyclonal antibody to CX3CL1 (Biotin).

This antibody recognises human fractalkine, otherwise known as CX3CL1, a 397 amino acid CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle.Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leucocytes, including T cells, monocytes and NK cells and fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes. CX3CL1 may also play a role in dendritic cell mediated host defense against invading pathogens such as Legionella pneumophila.

WB, ELISA

ELISA: 0.15 - 0.30 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human fractalkine.

Rabbit

Polyclonal

IgG

Biotin

Lyophilized

Reconstitute with 0.5 ml of sterile Phosphate Buffered Saline containing 0.1% Bovine Serum Albumin.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human Fractalkine antibody recognizes human fractalkine, otherwise known as CX3CL1, a 397 amino acid CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle.Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leucocytes, including T cells, monocytes and NK cells and fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes (Sunnemark et al. 2005). CX3CL1 may also play a role in dendritic cell mediated host defense against invading pathogens such as Legionella pneumophila (Kikuchi et al. 2005).

A 152E5.2, AB030188, ABCD 3, ABCD3, AI848747, C X3 C motif chemokine 1, C-X3-C motif chemokine 1, C3Xkine, Chemokine (C X3 C motif) ligand 1, Chemokine (C-X3-C motif) ligand 1, Chemokine C X3 C motif ligand 1, Chemokine CX3C Motif Ligand 1, CX3C membrane anchored chemokine, CX3C membrane-anchored chemokine, CXC 3, CXC3, CXC3C, D8Bwg0439e, FKN, Fractalkine, Neurotactin, NTN, NTT, Processed fractalkine, SCYD 1 , SCYD1, Small inducible cytokine D1, Small inducible cytokine subfamily D (Cys X3 Cys) member 1, Small inducible cytokine subfamily D (Cys X3 Cys), member 1, Small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) , Small inducible cytokine subfamily D member 1, Small-inducible cytokine D1, X3CL1_HUMAN

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.