Anti-Collagen VII Antibody [LH7.2] (A280875)

Anti-Collagen VII Antibody [LH7.2]

Mouse monoclonal [LH7.2] antibody to Collagen VII.

This antibody recognises the carboxy-terminus of type VII collagen. Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components. Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain. Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin.

IHC-Fr: 1:25 - 1:100

Human

This antibody does not cross react with Rat, Mouse, or Pig

Crude extract of skin.

Mouse

Monoclonal

LH7.2

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human collagen VII antibody, clone LH7.2 recognizes the carboxy-terminus of type VII collagen (Kirkham et al. 1989). Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components (Gammon et al. 1992). Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain.Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin (Watson et al. 2001).

COL7A1, Collagen alpha-1(VII) chain, LC collagen, Long-chain collagen