This antibody recognises the carboxy-terminus of type VII collagen. Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components. Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain. Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin.

Applications

IHC-Fr

Recommander des dilutions

IHC-Fr: 1:25 - 1:100

Reactivité

Human

Réactivité croisée

This antibody does not cross react with Rat, Mouse, or Pig

Immunogène

Crude extract of skin.

Hôte

Mouse

Clonalité

Monoclonal

Clone

LH7.2

Isotype

IgG1

Conjuguer

Unconjugated

Purification

Protein A affinity chromatography of tissue culture supernatant.

Concentration

1 mg/ml

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Mouse anti Human collagen VII antibody, clone LH7.2 recognizes the carboxy-terminus of type VII collagen (Kirkham et al. 1989). Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components (Gammon et al. 1992). Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain.Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin (Watson et al. 2001).

Synonymes

Alpha 1 type VII collagen, CO7A1_HUMAN, Col7a1, Collagen alpha 1(VII) chain, Collagen alpha-1(VII) chain, Collagen type VII alpha 1, Collagen VII alpha 1 polypeptide, CollagenVII, EBD 1, EBD1, EBDCT, EBR 1, EBR1, LC collagen, Long chain collagen, Long-chain collagen

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.