Anti-CD8 Antibody [MEM-31] (PE-Cyanine 7) (A122027)

Anti-CD8 Antibody [MEM-31] (PE-Cyanine 7)

Mouse monoclonal [MEM-31] antibody to CD8 (PE-Cyanine 7).

This antibody recognizes a conformationally-dependent extracellular epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 is a disulfide-linked dimer and exists as a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer (each monomer approx. 32-34 kDa). The antibody does not react with formaldehyde-fixed cells; negative in western blotting.

Flow Cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Human

Crude thymus membrane fraction.

Mouse

MEM-31

IgG2a

This antibody is conjugated with tandem dye PE-Cyanine 7 under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free fluorochrome.

32-34 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Shipped at 4°C. Store in the dark at 2-8°C. Do not freeze!

Activation B7-1 antigen, B7, BB1, CD28LG, CD28LG1, CD80, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80

This product is for research use only. It is not intended for diagnostic or therapeutic use.