Recombinant Anti-CD7 Anticorps [rCD7/6387] (A250550)

Anticorps monoclonal [rCD7/6387] de souris contre CD7 pour WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CD7 Antibody [rCD7/6387]
Description du produit
Recombinant mouse monoclonal [rCD7/6387] antibody to CD7.
Spécificité
This antibody recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Applications
WB, IHC-P
Recommander des dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 72-175, of human CD7 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rCD7/6387
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
40 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD7 Antibody [rCD7/6387] - BSA and Azide free (A253730).
Synonymes
CD7 antigen, CD7 antigen (p41), CD7 molecule, CD7_HUMAN, GP40, LEU 9, LEU9, p41 protein, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp 40, Tp40, TP41
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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