Anti-CD7 Anticorps [CD7/7605] (A316125)

Anti-CD7 Antibody [CD7/7605] - BSA and Azide free

Mouse monoclonal [CD7/7605] antibody to CD7.

Recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

WB, IHC-P

HePG-2 or Jurkat cells. Human lymph node or tonsil.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human CD7 protein. The exact sequence is proprietary.

Mouse

Monoclonal

CD7/7605

Unconjugated

Protein A/G chromatography.

1 mg/ml

40 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD7 antigen, CD7 antigen (p41), CD7 molecule, CD7_HUMAN, GP40, LEU 9, LEU9, p41 protein, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp 40, Tp40, TP41