Anti-CD63 Anticorps [MEM-259] (FITC) (A281143)

$145

Anticorps monoclonal [MEM-259] de souris contre CD63 (FITC) pour Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CD63 Antibody [MEM-259] (FITC)
Description du produit
Mouse monoclonal [MEM-259] antibody to CD63 (FITC).
Spécificité
This antibody recognises the CD63 cell surface antigen, also known as granulophysin, lysozomal associated membrane protein 3 (LAMP-3), Melanoma-associated antigen ME491, Ocular melanoma-associated antigen or tetraspanin-30. CD63 is a 238 amino acid, tetraspanin glycoprotein of ~40-60 kDa.CD63 is expressed by monocytes, macrophages, endothelial cells where it is a component of Weibel-Palade bodies and by a variety of cell lines. It is located intracellularly in lysosomal granules of platelets, being translocated to the surface upon activation. It may therefore by useful as a marker of platelet activation. CD63 expression is also associated with melanoma development and expression is rapidly down-regulated by progesterone in endometrial tissues.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl or 100µl whole blood
Reactivité
Human
Immunogène
HPB-ALL cell line.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MEM-259
Isotype
IgG1
Conjuguer

FITC

Excitation: 490nm, Emission: 525nm

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
100 µg/ml
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Notes générales
Mouse anti Human CD63 antibody, clone MEM-259 recognizes the CD63 cell surface antigen, also known as granulophysin, lysozomal associated membrane protein 3 (LAMP-3), Melanoma-associated antigen ME491, Ocular melanoma-associated antigen or tetraspanin-30. CD63 is a 238 amino acid, tetraspanin glycoprotein of ~40-60 kDa.CD63 is expressed by monocytes, macrophages, endothelial cells where it is a component of Weibel-Palade bodies (Vischer et al. 1993) and by a variety of cell lines. It is located intracellularly in lysosomal granules of platelets, being translocated to the surface upon activation. It may therefore by useful as a marker of platelet activation (Hamamoto et al. 1994). CD63 expression is also associated with melanoma development (Radford et al. 1997) and expression is rapidly down-regulated by progesterone in endometrial tissues (Okada et al. 1999).
Synonymes
CD 63, CD63 antigen, CD63 antigen (melanoma 1 antigen), CD63 antigen melanoma 1 antigen, CD63 molecule, CD63_HUMAN, gp55, Granulophysin, LAMP 3, LAMP-3, LAMP3, LIMP, Lysosomal associated membrane protein 3, Lysosomal-associated membrane protein 3, Lysosome associated membrane glycoprotein 3, Mast cell antigen AD1, ME491, Melanoma 1 antigen, Melanoma associated antigen ME491, Melanoma associated antigen MLA1, Melanoma-associated antigen ME491, MGC72893, MLA 1, MLA1, NGA, Ocular melanoma associated antigen, Ocular melanoma-associated antigen, OMA81H, PTLGP40, Tetraspanin 30, Tetraspanin-30, Tspan 30, Tspan-30, TSPAN30
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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