Anti-CD47 Anticorps [OX-101] (A281370)

Anti-CD47 Antibody [OX-101]

Mouse monoclonal [OX-101] antibody to CD47.

This antibody recognises the rat homologue of human CD47, also known as integrin associated protein (IAP). Rat CD47 is a 303 amino acid ?33 kDa multi pass transmembrane glycoprotein bearing a single V-type Ig-like domain and has been identified as the ligand for the rat signal regulatory protein, SIRP. Rat CD47 is expressed primarily by lymphocytes and macrophages but has also been detected at high levels on brain endothelial cells. Mouse anti Rat CD47 antibody, clone OX-101 has been reported to block the interaction of CD47 and SIRP.

WB, IP, Flow Cytometry

Flow Cytometry: 1:10 - 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Rat

Rat Thymocytes.

Mouse

Monoclonal

OX-101

IgG1

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Rat CD47 antibody, clone OX-101 recognizes the rat homologue of human CD47, also known as integrin associated protein (IAP). Rat CD47 is a 303 amino acid ?33 kDa multi pass transmembrane glycoprotein bearing a single V-type Ig-like domain and has been identified as the ligand for the rat signal regulatory protein, SIRP (Vernon-Wilson et al. 2000). Rat CD47 is expressed primarily by lymphocytes and macrophages but has also been detected at high levels on brain endothelial cells.Mouse anti Rat CD47 antibody, clone OX-101 has been reported to block the interaction of CD47 and SIRP (Vernon-Wilson et al. 2000).

Antigen identified by monoclonal, Antigenic surface determinant protein OA3, CD 47, CD47 antigen, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 glycoprotein, CD47 molecule, CD47_HUMAN, IAP, Integrin Associated Protein, Integrin associated signal transducer, Integrin-associated protein, Leukocyte surface antigen CD47, MER 6, MER6, OA 3, OA3, OTTHUMP00000041152, OTTHUMP00000041153, Protein MER6, Rh related antigen, Surface antigen identified by monoclonal