Anti-CD46 Anticorps [169-1-E4.3] (A252489)

Anticorps monoclonal [169-1-E4.3] de souris contre CD46 pour Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CD46 Antibody [169-1-E4.3] - BSA and Azide free
Description du produit
Mouse monoclonal [169-1-E4.3] antibody to CD46.
Spécificité
This antibody recognizes a protein of 52kDa-58kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human, Baboon
Réactivité croisée
This antibody does not react with Horse.
Immunogène
Stimulated human leukocytes.
Hôte
Mouse
Clonalité
Monoclonal
Clone
169-1-E4.3
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Concentration
1 mg/ml
Masse moléculaire
52-58 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD46 Antibody [169-1-E4.3] (A249309).
Synonymes
AHUS2, Antigen defined by monoclonal, Antigen identified by monoclonal, CD46 antigen, CD46 antigen complement regulatory protein, CD46 molecule, CD46 molecule complement regulatory protein, Complement membrane cofactor protein, MCP, MCP_HUMAN, Measles virus receptor, Membrane cofactor protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MGC26544, MIC10, TLX, TRA2.10, Trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, Trophoblast lymphocyte cross reactive antigen
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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