Anti-CD44v6 Anticorps [CD44v6/1246] (A250720)

Anti-CD44v6 Antibody [CD44v6/1246]

Mouse monoclonal [CD44v6/1246] antibody to CD44v6.

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

IHC-P

IHC-P: 1-2 µg/ml

Human

Recombinant fragment corresponding to the v6 domain of human CD44.

Mouse

Monoclonal

CD44v6/1246

IgG2a

kappa

Unconjugated

200 µg/ml

80-95 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD44v6 Antibody [CD44v6/1246] - BSA and Azide free (A253900).

CD44, CD44 antigen, CD44 molecule, CD44 molecule (Indian blood group), CD44_HUMAN, CDw44, Cell surface glycoprotein CD44, Chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCELL, Hematopoietic cell E and L selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, Homing function and Indian blood group system, HUTCH I, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, Soluble CD44