Anti-CD43 Anticorps [DFT-1] (PE) (A280249)

$515

Anticorps monoclonal [DFT-1] de souris contre CD43 (PE) pour Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CD43 Antibody [DFT-1] (PE)
Description du produit
Mouse monoclonal [DFT-1] antibody to CD43 (PE).
Spécificité
This antibody recognises human CD43 also known as leukosialin or sialophorin. CD43 is a 381 amino acid single pass type I transmembrane glycoprotein present on the cell surface of multiple cell types including thymocytes, T-lymphocytes, neutrophils, plasma cells and platelets. It is lacking on the surface of most B-lymphocytes. CD34 is a major membrane sialoglycoprotein expressed on T lymphocytes as two predominant glycoforms, a ~115 kDa form present on all T-cells and a ~130 kDa form indicative of T-cell activation and acts as a T-cell counter-receptor for CD169/Siglec-1. Mouse anti Human CD43 antibody, clone DFT-1 binds to both glycoforms of human CD43 CD34 expression is deficient and/or defective in patients suffering from the X-linked chromosomal immunodeficiency condition Wiskott-Aldrich syndrome and acts as a ligand for CD54. Mouse anti human CD43, clone DFT-1 has been used successfully for the evaluation of CD43 expression in patients with Myelodysplastic syndromes.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood
Reactivité
Human
Immunogène
KG-1 cells.
Hôte
Mouse
Clonalité
Monoclonal
Clone
DFT-1
Isotype
IgG1
Conjuguer

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
Reconstitution dependent.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water.
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Stockage
Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Mouse anti Human CD43 antibody, clone DFT-1 recognizes human CD43 also known as leukosialin or sialophorin. CD43 is a 381 amino acid single pass type I transmembrane glycoprotein present on the cell surface of multiple cell types including thymocytes, T-lymphocytes, neutrophils, plasma cells and platelets. It is lacking on the surface of most B-lymphocytes. CD34 is a major membrane sialoglycoprotein expressed on T lymphocytes as two predominant glycoforms, a ~115 kDa form present on all T-cells and a ~130 kDa form indicative of T-cell activation (Barren et al. 1997) and acts as a T-cell counter-receptor for CD169/Siglec-1 (van den Berg et al. 2001). Mouse anti Human CD43 antibody, clone DFT-1 binds to both glycoforms of human CD43 (Kyoizumi et al. 2004)CD34 expression is deficient and/or defective in patients suffering from the X-linked chromosomal immunodeficiency condition Wiskott-Aldrich syndrome and acts as a ligand for CD54 (Rosenstein et al. 1991). Mouse anti human CD43, clone DFT-1 has been used successfully for the evaluation of CD43 expression in patients with Myelodysplastic syndromes (Kyriakou et al. 2006).
Synonymes
CD 43, CD43 antigen, Galactoglycoprotein, GALGP, GPL 115, GPL115, Human gene for sialophorin, Leucocyte sialoglycoprotein, Leukocyte large sialoglycoprotein, Leukocyte sialoglycoprotein, Leukosialin, LEUK_HUMAN, LSN, Ly-48, Sialophorin, sialophorin (gpL115, leukosialin, CD43), Spn
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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