Anti-CD34 Anticorps [ICO-115] (CF® 647) (A251165)

Ce produit est discontinué

Anti-CD34 Anticorps [ICO-115] (CF® 647) (A251165) a été abandonné et n'est plus disponible.

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Nom du produit
Anti-CD34 Antibody [ICO-115] (CF® 647)
Description du produit
Mouse monoclonal [ICO-115] antibody to CD34 (CF® 647).
Spécificité
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 5 µl / million cells or 5 µl / 100 µl whole blood, IF: 1:50-1:100
Reactivité
Human, Rat
Immunogène
Blast cells of a chronic myeloid leukemia patient.
Hôte
Mouse
Clonalité
Monoclonal
Clone
ICO-115
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

CF® 647

Excitation: 650nm, Emission: 665nm

Purification
Protein A/G chromatography.
Concentration
100 µg/ml
Masse moléculaire
90-110 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Store at 4-8°C. Antibody is stable for 24 months.
Synonymes
CD34 antigen, CD34 molecule, CD34_HUMAN, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, Mucosialin, OTTHUMP00000034733, OTTHUMP00000034734
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
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