Anti-CD30 Antibody [Ki-1/4399R] - BSA and Azide free
Description du produit
Recombinant rabbit monoclonal [Ki-1/4399R] antibody to CD30.
Spécificité
This antibody recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Applications
IHC
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human CD30 protein.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
Ki-1/4399R
Isotype
IgG
Chaînes légères
kappa
Conjuguer
Unconjugated
Purification
Protein A chromatography.
Concentration
1 mg/ml
Masse moléculaire
105-120 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.