Anti-CD146 Anticorps [MCAM/3046] (A249295)

Anticorps monoclonal [MCAM/3046] de souris contre CD146 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CD146 Antibody [MCAM/3046]
Description du produit
Mouse monoclonal [MCAM/3046] antibody to CD146.
Spécificité
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 226-374, of human MCAM protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
MCAM/3046
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
130 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD146 Antibody [MCAM/3046] - BSA and Azide free (A252475).
Synonymes
A32 antigen, CD 146, CD146 antigen, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Gicerin, Mcam, Melanoma adhesion molecule, Melanoma associated antigen A32, Melanoma associated antigen MUC18, Melanoma associated glycoprotein MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MelCAM, MUC 18, MUC18, MUC18_HUMAN, S endo 1, S endo 1 endothelial associated antigen, S-endo 1 endothelial-associated antigen
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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