Anti-CD11c Anticorps [BAQ153A] (A279780)

$355

Anticorps monoclonal [BAQ153A] de souris contre CD11c pour Flow Cytometry et ICC.

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CD11c Antibody [BAQ153A]
Description du produit
Mouse monoclonal [BAQ153A] antibody to CD11c.
Spécificité
This antibody recognises bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection. Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC and flow cytometry.
Applications
Flow Cytometry, ICC
Recommander des dilutions
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivité
Bovine, Goat, Sheep, Bison, Water Buffalo
Immunogène
Cells from multiple species.
Hôte
Mouse
Clonalité
Monoclonal
Clone
BAQ153A
Isotype
IgM
Conjuguer

Unconjugated

Purification
0.2µM sterile filtered.
Concentration
1 mg/ml
Forme du produit
Liquid
Formulation
Supplied in serum free tissue culture medium containing proprietary protein free supplement and 0.09% Sodium Azide.
Stockage
Store at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Mouse anti Bovine CD11c, clone BAQ153A, recognizes bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection (Sei et al. 2016). Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC (Palmer et al. 2011) and flow cytometry (Sei et al. 2016).
Synonymes
95, 95 alpha chain, CD 11c, CD11 antigen like family member C, CD11 antigen-like family member C, CD11c antigen, Complement component 3 receptor 4 subunit, CR4, Integrin alpha X, Integrin alpha X chain, Integrin alpha-X, Integrin aX, Integrin subunit alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit, ITAX_HUMAN, ITGAX, Leu M5, LEU M5 alpha subunit, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150, Leukocyte adhesion receptor p150 95, Leukocyte surface antigen p150 95 alpha subunit, Leukocyte surface antigen p150 alpha subunit, Myeloid membrane antigen alpha subunit, p150, p150 95 integrin alpha chain, p150/95, SLEB6
Contrôles isotype
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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