This antibody recognises calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK II alpha) also known as CaM kinase II subunit alpha, when phosphorylated at threonine 286. CaMK II alpha is a member of the CAMK serine/threonine protein kinase family involved in the central nervous system, neurotransmitter release and synaptic plasticity.CaMK II alpha is activated upon binding of calcium/calmodulin, resulting in autophosphorylation at threonine 286.

Applications

Recommander des dilutions

WB: 1:500 - 1:2,000

Reactivité

Human, Mouse, Rat

Immunogène

Phospho-specific peptide corresponding to residues surrounding Thr286 of human CaMK II alpha.

Hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Conjuguer

Unconjugated

Concentration

Lot Specific

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Stockage

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Notes générales

Rabbit anti CaMK II alpha (pThr286) antibody recognizes calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK II alpha) also known as CaM kinase II subunit alpha, when phosphorylated at threonine 286. CaMK II alpha is a member of the CAMK serine/threonine protein kinase family involved in the central nervous system, neurotransmitter release and synaptic plasticity.CaMK II alpha is activated upon binding of calcium/calmodulin, resulting in autophosphorylation at threonine 286.

Synonymes

Alpha CaMKII, Calcium calmodulin dependent protein kinase II, Calcium/calmodulin dependent protein kinase II alpha B subunit, Calcium/calmodulin dependent protein kinase type II alpha chain, Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, Calcium/calmodulin-dependent protein kinase II alpha, Calcium/calmodulin-dependent protein kinase II-alpha, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase type IIA, CaM kinase II alpha chain, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CaMK II alpha subunit, CaMK-II subunit alpha, Camk2a, CAMKA, CaMKII, CaMKIINalpha, EC 2.7.11.17, KCC2A_HUMAN, KIAA0968, MGC123320, MGC139375, MGC155201, mKIAA0968, PK2CDD, PKCCD, R74975, zgc:112538, zgc:123320

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.