Anti-C5a-R Anticorps [20/70] (PE) (A279123)

$515

Anticorps monoclonal [20/70] de rat contre C5a-R (PE) pour Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-C5a-R Antibody [20/70] (PE)
Description du produit
Rat monoclonal [20/70] antibody to C5a-R (PE).
Spécificité
This antibody recognises mouse CD88, also known as C5a anaphylatoxin chemotactic receptor 1 (C5aR1), a member of the G-protein coupled receptor 1 family. CD88 is a ~45 kDa multi pass membrane protein and functions as a receptor for the complement component C5a, a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Rat anti Mouse CD88 antibody, clone 20/70 is able to block the binding of the C5a to murine CD88,.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl.The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/B).
Reactivité
Mouse
Immunogène
RBL-2H3 transfected cells expressing mouse C5aR.
Hôte
Rat
Clonalité
Monoclonal
Clone
20/70
Isotype
IgG2b
Conjuguer

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
Reconstitution dependent.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water.
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Stockage
Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Rat anti Mouse CD88 antibody, clone 20/70 recognizes murine CD88, also known as C5a anaphylatoxin chemotactic receptor 1 (C5aR1), a member of the G-protein coupled receptor 1 family. CD88 is a ~45 kDa multi pass membrane protein and functions as a receptor for the complement component C5a, a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Rat anti Mouse CD88 antibody, clone 20/70 is able to block the binding of the C5a to murine CD88, (Soruri et al. 2003).
Synonymes
ANAPHYLATOXIN RECEPTOR, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin receptor, C5a ligand, C5aR, c5ar1, C5AR_HUMAN, C5R1, CD88, CD88 antigen, Complement component 5 receptor 1, Complement component 5 receptor 2, Complement component 5a receptor 1
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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