Anti-C3d Antibody [C3D/2891] (A250214)

Mouse monoclonal [C3D/2891] antibody to C3d for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-C3d Antibody [C3D/2891]
Description
Mouse monoclonal [C3D/2891] antibody to C3d.
Specificity
The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response through the interaction with complement receptor type 2 (CR2). CR2 is important in the switched-isotype, high-affinity and memory humoral immune responses to T-dependent foreign antigens, as well as in the development of the natural antibody repertoire. This pH- and ionic strength-dependent association of C3d with CR2 represents a link between innate and adaptive immunity.
Applications
ELISA
Reactivity
Human
Immunogen
Recombinant full-length human Complement C3 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
C3D/2891
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
35 kDa (predicted)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-C3d Antibody [C3D/2891] - BSA and Azide free (A253394).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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