This antibody recognises human C-reactive protein (CRP), a calcium-binding plasma protein which is significantly up-regulated during the acute phase response. CRP has been shown to bind phosphocholine residues, apoptotic cells and constituents of micro-organisms, and can lead to activation of leukocytes and the complement system, and the clearance of apoptotic cells.CRP is produced in the liver in response to interleukin-1 (IL-1) and IL-6 secretion, and has a monomer molar mass of 25 kDa, and native cyclic pentamer mass of 125 kDa.
Applications
ELISA, IHC-Fr
Reactivité
Human
Immunogène
Native c-reactive protein from serum.
Hôte
Sheep
Clonalité
Polyclonal
Isotype
IgG
Conjuguer
Unconjugated
Concentration
5 mg/ml
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Notes générales
Sheep anti Human C-Reactive Protein antibody detects human C-reactive protein (CRP), a calcium-binding plasma protein which is significantly up-regulated during the acute phase response. CRP has been shown to bind phosphocholine residues, apoptotic cells and constituents of micro-organisms, and can lead to activation of leukocytes and the complement system, and the clearance of apoptotic cells.CRP is produced in the liver in response to interleukin-1 (IL-1) and IL-6 secretion, and has a monomer molar mass of 25 kDa, and native cyclic pentamer mass of 125 kDa.
Synonymes
C reactive protein pentraxin related, C-reactive protein(1-205), CRP, CRP_HUMAN, MGC88244, Pentraxin 1, Pentraxin 1, short, PTX 1, PTX1