Mouse monoclonal [BRIC203] antibody to Blood Group Kell Antigen.
Spécificité
This antibody recognises human CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on the ~93 kDa erythrocyte membrane glycoprotein.In hemagglutination tests, Mouse anti Human CD238 antibody, clone BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition Mouse anti Human CD238 antibody, clone BRIC203 will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko erythrocytes. Weaker staining in flow cytometry is observed on erythroblasts derived from CD34+ hematopoietic progenitor cells, compared to Kp (a-b+) red blood cells.
Applications
Flow Cytometry, IP, Haemagglutination
Recommander des dilutions
Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivité
Human
Immunogène
Human erythrocytes.
Hôte
Mouse
Clonalité
Monoclonal
Clone
BRIC203
Isotype
IgG1
Conjuguer
Unconjugated
Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Forme du produit
Liquid
Formulation
Supplied in TRIS Buffered Saline with <0.1% Sodium Azide and =100mM glycine.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Notes générales
Mouse anti Human CD238 antibody, clone BRIC203 recognizes human CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on the ~93 kDa erythrocyte membrane glycoprotein.In hemagglutination tests, Mouse anti Human CD238 antibody, clone BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition Mouse anti Human CD238 antibody, clone BRIC203 will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko erythrocytes. Weaker staining in flow cytometry is observed on erythroblasts derived from CD34+ hematopoietic progenitor cells, compared to Kp (a-b+) red blood cells.
Synonymes
CD238, CD238 antigen, ECE3, kel, Kell blood group, Kell blood group glycoprotein, Kell blood group metallo endopeptidase, Kell blood group metalloendopeptidase, KELL NULL, Kell protein, KELL_HUMAN
