Recombinant rabbit monoclonal [DM16] antibody to BCMA.
Applications
Flow Cytometry, MM Tumor cell killing
Recommander des dilutions
Flow Cytometry: 1:100
Reactivité
Human
Hôte
Rabbit
Clonalité
Monoclonal
Clone
DM16
Isotype
scFv
Conjuguer
Unconjugated
Purification
Affinity chromatography.
Concentration
Reconstitution dependent.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with distilled sterile water.
Formulation
Lyophilized from sterile Phosphate Buffered Saline, pH 7.4. Normally 5%–8% Trehalose is added as a protectant before lyophilization.
Stockage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
Notes générales
Prior to reconstitution, centrifuge the vial at 5,000g for 3-5 minutes at room temperature. Reconstitute with appropriate volume of distilled sterile water to bring product to 1mg/ml concentration. After addition of distilled sterile water, mix by gentle tapping. Note: It is not recommended to vortex or vigorously pipette the sample.
Synonymes
B cell maturation antigen, B cell maturation factor, B cell maturation protein, B-cell maturation protein, BCM, CD269, CD269 antigen, TNFRSF17, TNR17_HUMAN, Tumor necrosis factor receptor superfamily member 17
The basic principle of BiTE cell killing assay. The BiTE molecule can effectively bring T cells to tumor target cells and stimulate tumor cell killing activity of T cells.
A. The scheme of Anti-BCMA BiTE molecule. B. Tumor cell killing assay. NCI-H929 cells (stably transfected with luciferase), were incubated with freshly isolated Human PBMC, and different concentration of BiTE antibodies constructed from Anti-BCMA Antibody [DM16] - Azide free (A318801) (red line) or BB2121 originated huC11D5.3 clone (blue line) or a no BCMA binding clone as negative control (black line). After 48hrs incubation, the viable NCI-H929 tumor cells were measured by luciferase activity assay.
Produits alternatifs à Anti-BCMA Anticorps [DM16] (A318801)
![BiTE Cell Killing Assay - Anti-BCMA Antibody [DM16] - Azide free (A318801) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318801_1.png?profile=product_top)
![Flow Cytometry - Anti-BCMA Antibody [DM16] - Azide free (A318801) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318801_3.jpg?profile=product_top)
![BiTE Cell Killing Assay - Anti-BCMA Antibody [DM16] - Azide free (A318801) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318801_1.png?profile=product_top_thumb)
![Flow Cytometry - Anti-BCMA Antibody [DM16] - Azide free (A318801) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318801_3.jpg?profile=product_top_thumb)
![BiTE Cell Killing Assay - Anti-BCMA Antibody [DM16] - Azide free (A318801) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318801_1.png?profile=product_image)
![Flow Cytometry - Anti-BCMA Antibody [DM16] - Azide free (A318801) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318801_3.jpg?profile=product_image)
![Flow Cytometry - Anti-BCMA Antibody [DM4] - BSA and Azide free (A318679) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318679_1.jpg?profile=product_alternative)
![Flow Cytometry - Anti-BCMA Antibody [DM6] - BSA and Azide free (A318678) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318678_1.jpg?profile=product_alternative)
![Flow Cytometry - Anti-BCMA Antibody [DM16] - Azide free (A318668) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318668_1.png?profile=product_alternative)
![Immunohistochemistry - Anti-BCMA Antibody [BCMA/2366] (A249910) - Antibodies.com](https://cdn.antibodies.com/image/catalog/249/A249910_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-BCMA Antibody [BCMA/2366] - BSA and Azide free (A253090) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253090_1.jpg?profile=product_alternative)
![ELISA - Anti-BCMA Humanized Antibody [Biosimilar] - Azide free (A318940) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318940_1.png?profile=product_alternative)
![BiTE Cell Killing Assay - Anti-BCMA Antibody [DM4] - Azide free (A318802) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318802_1.png?profile=product_alternative)
![ELISA - Anti-BCMA Humanized Antibody [Belantamab Biosimilar] - Azide free (A318928) - Antibodies.com](https://cdn.antibodies.com/image/catalog/318/A318928_1.png?profile=product_alternative)
