Anti-Androgen Receptor Anticorps [AR441] (A249053)

Anticorps monoclonal [AR441] de souris contre Androgen Receptor pour Flow Cytometry, IF et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Androgen Receptor Antibody [AR441]
Description du produit
Mouse monoclonal [AR441] antibody to Androgen Receptor.
Spécificité
This antibody recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
Applications
Flow Cytometry, IF, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Réactivité croisée
This antibody does not cross react with Mouse.
Immunogène
Synthetic peptide corresponding to amino acids 302-318 of human Androgen Receptor.
Séquence
STEDTAEYSPFKGGYTK
Hôte
Mouse
Clonalité
Monoclonal
Clone
AR441
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
110 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Androgen Receptor Antibody [AR441] - BSA and Azide free (A252233).
Synonymes
AIS, Androgen nuclear receptor variant 2, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), androgen receptor splice variant 4b, ANDR_HUMAN, AR, AR8, DHTR, Dihydro testosterone receptor, Dihydrotestosterone receptor, Dihydrotestosterone receptor (DHTR), HUMARA, HYSP1, KD, Kennedy disease (KD), NR3C4, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), SBMA, SMAX1, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Testicular Feminization (TFM), TFM
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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