Anti-Alkaline Phosphatase, Tissue Non-Specific Anticorps [V17.1] (A248637)

Anticorps monoclonal [V17.1] de souris contre Alkaline Phosphatase, Tissue Non-Specific pour Flow Cytometry, IF et IHC-Fr.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [V17.1]
Description du produit
Mouse monoclonal [V17.1] antibody to Alkaline Phosphatase, Tissue Non-Specific.
Spécificité
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Applications
Flow Cytometry, IF, IHC-Fr
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-Fr: 1-2 µg/ml
Reactivité
Human, Bovine
Immunogène
Bovine intestinal alkaline phosphatase.
Hôte
Mouse
Clonalité
Monoclonal
Clone
V17.1
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
55 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [V17.1] - BSA and Azide free (A251819).
Synonymes
AKP2, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, Alkaline phosphatase, tissue-nonspecific isozyme, Alkaline phosphomonoesterase, Alpl, AP TNAP, AP-TNAP, APTNAP, BAP, FLJ40094, FLJ93059, Glycerophosphatase, HOPS, Liver/bone/kidney type alkaline phosphatase, MGC161443, MGC167935, PHOA, PPBT_HUMAN, Tissue non specific alkaline phosphatase, Tissue nonspecific ALP, TNAP, TNSALP
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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