Anti-ALDH1L1 Anticorps [ALDH1L1/7701] (A315825)

$765

Anticorps monoclonal [ALDH1L1/7701] de souris contre ALDH1L1 pour WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-ALDH1L1 Antibody [ALDH1L1/7701] - BSA and Azide free
Description du produit
Mouse monoclonal [ALDH1L1/7701] antibody to ALDH1L1.
Spécificité
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1L1 (aldehyde dehydrogenase 1 family member L1), also known as FTHFD or 10-FTHFD (10-formyltetrahydrofolate dehydrogenase), is a cytosolic protein that is developmentally regulated in the cerebellum. ALDH1L1 binds to folate and catalyzes the conversion of 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF). This suggests a possible role for ALDH1L1 in the regulation of cellular THF levels as well as in the inhibition of cell proliferation (as 10-FTHF is essential for the synthesis of purine). In addition, the overexpression of ALDH1L1 can restrict cell proliferation in vitro.
Applications
WB, IHC-P
Contrôle positif
Human kidney or liver. A549 or SK-BR3 cells.
Recommander des dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment of human ALDH1L1 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
ALDH1L1/7701
Isotype
IgG
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
99 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
10 formyltetrahydrofolate dehydrogenase, 10 FTHFDH, 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, AL1L1_HUMAN, Aldehyde dehydrogenase 1 family member L1, Aldehyde dehydrogenase family 1 member L1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, DKFZp781N0997, EC 1.5.1.6, FDH, formyltetrahydrofolate dehydrogenase, FTHFD, OTTHUMP00000155221, OTTHUMP00000214696, OTTHUMP00000214700, OTTHUMP00000222724
Contrôles isotype
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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