Anti-ABCA1 Anticorps [5A1-1422] (PE) (A279415)

$515

Anticorps monoclonal [5A1-1422] de rat contre ABCA1 (PE) pour Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-ABCA1 Antibody [5A1-1422] (PE)
Description du produit
Rat monoclonal [5A1-1422] antibody to ABCA1 (PE).
Spécificité
This antibody recognises mouse adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease.Mutations in ABCA1 gene have been associated with Tangier disease, a genetic disorder of lipid metabolism, and the more common Familial HDL deficiency, peresenting with many of the same symproms.
Applications
Flow Cytometry
Recommander des dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.
Reactivité
Mouse
Immunogène
ABCA1 transfected HeLa cells.
Hôte
Rat
Clonalité
Monoclonal
Clone
5A1-1422
Isotype
IgG2a
Conjuguer

PE

Excitation: 565nm, Emission: 578nm

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
Reconstitution dependent.
Forme du produit
Lyophilized
Reconstitution
Reconstitute with 1 ml of distilled water
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Stockage
Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Notes générales
Rat anti Mouse ABCA1 antibody, clone 5A1.1422 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease.Mutations in ABCA1 gene have been associated with Tangier disease, a genetic disorder of lipid metabolism, and the more common Familial HDL deficiency, peresenting with many of the same symproms.
Synonymes
ABC 1, ABC Transporter 1, ABC-1, ABC1, ABCA 1, ABCA1_HUMAN, ATP binding Cassette 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding Cassette Transporter 1, ATP-binding cassette 1, ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, CERP, Cholesterol efflux regulatory protein, FLJ14958, HDLDT1, Membrane bound, MGC164864, MGC165011, TD, TGD
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.
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