Anti-14-3-3 Sigma Antibody [CPTC-SFN-2] (A248746)

Mouse monoclonal [CPTC-SFN-2] antibody to 14-3-3 Sigma for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-14-3-3 Sigma Antibody [CPTC-SFN-2]
Description
Mouse monoclonal [CPTC-SFN-2] antibody to 14-3-3 Sigma.
Specificity
SFN (stratifin) is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.
Applications
WB, IHC-P
Dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human SFN protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
CPTC-SFN-2
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
28 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-14-3-3 Sigma Antibody [CPTC-SFN-2] - BSA and Azide free (A251928).
Synonyms
14-3-3 protein sigma, Epithelial cell marker protein 1, HME1, SFN, Stratifin
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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