Recombinant Anti-FOXP1 Antibody [rFOXP1/6902] (A277889)

Name: Anti-FOXP1 Antibody [rFOXP1/6902]
Brand: Antibodies.com
SKU: A277889
Price: 525.0 USD
Availability: InStock

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$525

Recombinant mouse monoclonal [rFOXP1/6902] antibody to FOXP1 for IHC-P.

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Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

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Recombinant Antibody

Specifications

Name

Anti-FOXP1 Antibody [rFOXP1/6902]

Description

Recombinant mouse monoclonal [rFOXP1/6902] antibody to FOXP1.

Specificity

Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( 80%) for FOXP1 is needed to achieve high specificity for the ABC subtype.

Applications

IHC-P

Dilutions

IHC-P: 1-2 µg/ml

Reactivity

Human

Immunogen

Recombinant fragment, around amino acids 350-450, of human FOXP1 protein. The exact sequence is proprietary.

Host

Mouse

Clonality

Monoclonal

Clone ID

rFOXP1/6902

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Molecular Weight

75 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-FOXP1 Antibody [rFOXP1/6902] - BSA and Azide free (A278477).

Synonyms

12CC4, FLJ23741, Fork head related protein like B, Forkhead box P1, Forkhead box protein P1, FOX P1, FOXP 1, FOXP1_HUMAN, Glutamine rich factor 1, hFKH1B, HSPC215, MGC12942, MGC88572, MGC99551, QRF 1, QRF1

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

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Figure 1: Immunohistochemistry - Anti-FOXP1 Antibody [rFOXP1/6902] (A277889)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate carcinoma tissue using Anti-FOXP1 Antibody [rFOXP1/6902].

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Figure 2: Immunohistochemistry - Anti-FOXP1 Antibody [rFOXP1/6902] (A277889)

Negative Tissue Control: Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain using Anti-FOXP1 Antibody [rFOXP1/6902] at 1µg/ml in PBS for 30 minutes at room temperature.

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Figure 3: SDS-PAGE - Anti-FOXP1 Antibody [rFOXP1/6902] (A277889)

SDS-PAGE analysis of Anti-FOXP1 Antibody [rFOXP1/6902] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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