Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448)

Name: Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free
Brand: Antibodies.com
SKU: A323448
Price: 295.0 USD
Availability: InStock

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$295

Recombinant human monoclonal antibody to ICOS for ELISA, FACS, Functional Assay and In Vivo.

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Delivery

Freight Charges

$40 to United States

Lead Time

7-10 Business Days

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Telephone

+1 (314) 370-6046

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Recombinant Antibody

Specifications

Name

Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free

Description

Recombinant human monoclonal antibody to ICOS.

Applications

ELISA, FACS, Functional Assay, In Vivo

Reactivity

Human, Cynomolgus Macaque

Host

Human

Clonality

Monoclonal

Isotype

IgG4PE - Human IgG4 with S228P and L235E mutations

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A affinity chromatography.

Concentration

Reconstitution dependent.

Molecular Weight

This antibody has a predicted MW of 145.52 kDa.

Purity

> 95% (by SDS-PAGE and SEC-HPLC).

Product Form

Lyophilized

Reconstitution

Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!

Formulation

Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.

Storage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonyms

Activation inducible lymphocyte immunomediatory molecule, Activation-inducible lymphocyte immunomediatory molecule, AILIM, CD278, CD278 antigen, CD28-related Protein-1, CRP1, CVID1, ICOS_HUMAN, Inducible costimulator, Inducible T cell co stimulator, Inducible T-cell costimulator, MGC39850

Suitable Secondaries

See all Anti-Human IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

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Figure 1: SDS-PAGE - Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448)

SDS-PAGE analysis of Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.

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Figure 2: Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448)

SEC-HPLC analysis of Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448) confirms that the purity of this antibody is 99.12%.

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Figure 3: Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448)

Immobilized recombinant human ICOS protein (Fc tag) at 2 µg/ml is bound by Feladilimab Biosimilar - Anti-ICOS Antibody - Low endotoxin, Azide free (A323448). EC₅₀ = 0.09127 µg/ml.

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