Anti-Fas Ligand Antibody [10F2] (A278949)

$340

Mouse monoclonal [10F2] antibody to Fas Ligand for IP, Flow Cytometry and ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Fas Ligand Antibody [10F2]
Description
Mouse monoclonal [10F2] antibody to Fas Ligand.
Specificity
This antibody recognises the human CD178 cell surface antigen, a ~40 kDa glycoprotein also known as Fas ligand (CD95L).CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis. Mouse anti Human CD178 antibody, clone 10F2 is reported to block the activity of Fas ligand.
Applications
IP, Flow Cytometry, ELISA
Dilutions
Flow Cytometry: 1:25 - 1:50, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone ID
10F2
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human CD178 antibody, clone 10F2 recognizes the human CD178 cell surface antigen, a ~40 kDa glycoprotein also known as Fas ligand (CD95L).CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis. Mouse anti Human CD178 antibody, clone 10F2 is reported to block the activity of Fas ligand (Legembre et al. 2002).
Synonyms
ALPS1B, Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand, Apoptosis antigen ligand 1, APT1LG1, APTL, CD178, CD178 antigen, CD95 L, CD95 ligand, CD95-L, CD95L, CD95L protein, Fas antigen ligand, Fas L, Fas ligand (TNF superfamily member 6), FASL, Fasl Fas ligand (TNF superfamily member 6), FASLG, Generalized lymphoproliferative disease, Gld, soluble form, TNF superfamily member 6, TNFL6_HUMAN, TNFSF6, Tumor necrosis factor (ligand) superfamily member 6, Tumor necrosis factor ligand superfamily member 6
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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