Anti-ERCC1 Antibody [ERCC1/7596] - BSA and Azide free (A316306)

$765

Mouse monoclonal [ERCC1/7596] antibody to ERCC1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ERCC1 Antibody [ERCC1/7596] - BSA and Azide free
Description
Mouse monoclonal [ERCC1/7596] antibody to ERCC1.
Specificity
Recognizes a protein of 110kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
Applications
IHC-P
Positive Control
HeLa or HepG2 cells. Tonsil or Prostate.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 191-281) of human ERCC1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
ERCC1/7596
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
110 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
COFS 4, COFS4, DNA excision repair protein ERCC 1, DNA excision repair protein ERCC-1, DNA excision repair protein ERCC1, ERCC 1, ERCC1_HUMAN, Excision repair cross complementation group 1, Excision repair cross complementing 1, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1, Excision repair protein, RAD 10, RAD10, UV 20, UV20
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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