Anti-EIF4A2 Antibody [PCRP-EIF4A2-2B5] (A248415)

Mouse monoclonal [PCRP-EIF4A2-2B5] antibody to EIF4A2 for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-EIF4A2 Antibody [PCRP-EIF4A2-2B5]
Description
Mouse monoclonal [PCRP-EIF4A2-2B5] antibody to EIF4A2.
Specificity
Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a5 cap, eIF4A (I, II) are bidirectional RNA helicases, and eIF4G (I, II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.
Applications
ELISA
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Chicken, Mouse, Rat, Xenopus, and Zebrafish.
Immunogen
Recombinant full-length human EIF4A2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-EIF4A2-2B5
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
46 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-EIF4A2 Antibody [PCRP-EIF4A2-2B5] - BSA and Azide free (A251597).
Synonyms
ATP dependent RNA helicase eIF4A 2, ATP-dependent RNA helicase eIF4A-2, BM-010, DDX2B, eIF 4A II, eIF-4A-II, EIF4A, eIF4A II, eIF4A-II, EIF4F, Eukaryotic initiation factor 4A II, Eukaryotic initiation factor 4A-II, eukaryotic translation initiation factor 4A isoform 2, Eukaryotic translation initiation factor 4A2, IF4A2_HUMAN, N-terminally processed
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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